ALLERGY AND CLINICAL IMMUNOLOGY FOR DUMMIES

Yet another DNA-centered strategy has long been to combine allergen with bacterial DNA sequences that comprise CpG motifs to selectively target Toll-like receptor nine (TLR9) expressed on human B cells and dendritic cells. The key ragweed pollen allergen Amb a 1 covalently linked to a B-style CpG-containing oligodeoxynucleotide (ODN)131 was success